Symposium Program

8:00

Anti-PF4 induced thrombotic disorders Edelgard Lindhoff-Last. CardioAngiology Center Bethanienhospital (CCB), Head of the CCB Coagulations Center and CCB Coagulation Research Center, Frankfurt, Germany

8:30

Acquired Von Willebrand Disease Jeroen Eikenboom. Leiden University Medical Center

9:00

Platelet response to Dengue virus infection Martha Viveros. Universidad Michoacana de San NicolAis de Hidalgo

8:00

Newly Generated HbA2 Certified Material Cornelis L. Harteveld.

8:30

Monitoring Argatroban Susan Guy. Sheffield Thrombosis and Haemostasis Centre

9:00

Standardisation and validation of fms-like tyrosine kinase 3 internal tandem duplication measurable residual disease by ultra-sensitive next generation sequencing Aditya Tedjaseputra. King's College London

10:00

Standardisation and Validation of MRD Panels Marie-Christine BENE. Nantes University

10:30

Euroflow EQA program Jacques van Dongen. ESLHO EuroFlow, Zutphen, Netherlands

11:00

Nanobodies as potential tools for platelet diagnostics Rolf Urbanus. University Medical Center Utrecht

10:00

Molecular genetics of eosinophilia Dong Chen. University of Connecticut

10:30

Histiocytic tumors Zenggang Pan. University of Colorado

11:00

VEXAS syndrome screening Marion Eveillard. CHU de Nantes

1:00

Automated Reticulocyte Enumeration Using Machine Learning on Smartphone Microscopic Images for Low-Resource Settings Amit Nisal1, Arnav Nisal2. 1Bharati Vidyapeeth (DTU) Medical College Hospital and Research Centre, Pune, India.2DES Pune University, Pune, India

1:15

Correction of Platelet Count Bias in EDTA-PTCP by Reconstructing the Spatial Distribution of Platelets Meng Yang1, 2, Huixian Luo1, 2, Jiayi Ouyang1, 2, 4, Yong Chen3, Zipei Lin1, 2, Qiongyun Lin1, 2, Linjing Wang1, 2, Yantao Wang1, 2, Honglin Chen1, 2, Yi Zhang1, 2, Yinjuan MO1, 2, Enzhong Chen1, 2, Guangqing Lin1, 2, Xuedong Chen1, 2, Yan Liu3, Yonghui Guo1, 2. 1Department of Laboratory Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou China.2Guangdong Provincial Clinical Research Center for Laboratory Medicine, Guangdong China.3Shenzhen Mindray Bio- Medical Electronics Co. Ltd, Shenzhen China.4Southern Medical University, Guangdong China

1:30

Diagnostic value of Clauss/Antigen Fibrinogen ratio in patients with congenital fibrinogen disorders Tiago Luis, Dalila MarquesJoana Rita, Ana Campos, Laura Rodrigues, Goncalo Orfao, Nelya Syamro, Olena Lavrukhina, Marco Matias, Jorge Tomaz. Congenital Coagulopathies Reference Centre-RamA³n Salvado, Thrombosis and Haemostasis Unit, Blood Bank and Transfusion Medicine, Coimbra, Portugal

1:45

Flow cytometric cell sorting to enable genetic analysis in hematological neoplasms Veronika Ecker1, Nicola Goetz1, Marietta Truger1, Manuela Harloff1, Johannes Waldschmidt2, Leo Rasche2, Chrysanthi Tsamadou1, Gregor Hoermann1, Wolfgang Kern1. 1MLL Munich Leukemia Laboratory, Munich, Germany.2Department of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany

2:00

Laboratory monitoring in CAR-T cell therapy Nicola Maciocia. UCL

2:30

Genetic Basis of Bleeding Disorders Keith Gomez. Royal Freee London NHS Foundation Trust

3:00

Application of artificial intelligence in hemostasis Michael Nagler. Inselspital, Bern University Hospital, and University of Bern

4:00

Automated detection of red blood cell abnormalities in peripheral blood smears using SAM and ResNet Kevin Barrera2, Carmen Navarro4, A Molina1, JosAc Rodellar3, Anna Merino1. 1CORE Laboratory. Biochemistry and Molecular Genetics Department. Biomedical Diagnostic Center. Hospital Clinic, Barcelona, Spain.2Control, Data and Artificial Intelligence (CoDAlab), Department of Mechanical Engineering, Escola da, Barcelona, Spain.3Control, Data and Artificial Intelligence (CoDAlab), Department of Mathematics, Escola da, Barcelona, Spain.4Bioinformatics and Biostatistics, Universitat Oberta de Catalunya (UOC), Barcelona, Spain

4:12

Epigenetic and Immunologic Landscape of VSIR across Hematological Malignancies: Implications for Precision Immunotherapy Zijun Xu1, Xiaomei Wu2, Ran Chang1, Haoyu Cao1, Fei Wang1, Xiangmei Wen1, Jingdong Zhou1, Jiang Lin1, Jun Qian1. 1Affiliated Peoplea, Zhenjiang, Spain.2Zhenjiang College, Zhenjiang, China

4:24

Real-time CAR T-cell monitoring: Sysmex-XR Cell Population Data and Digital Morphology for Early Detection of Immune Activation and Clinical Complications Anna Merino1, Alex Calvera1, Angel Molina1, Nuria MartAsnez-CibriAin2, Nil Albiol2, Aina Oliver2, Julio Delgado2, Carlos FernAindez de Larrea2, ValentAsn Ortiz-Maldonado2. 1CORE Laboratory. Biochemistry and Molecular Genetics Department. Biomedical Diagnostic Center. Hospital Clinic of Barcelona-IDIBAPS, Barcelona, Spain.2Hematology Department, Institute of Cancer and Blood Diseases. Hospital Clinic of Barcelona-IDIBAPS, Barcelona, Spain

4:36

Analytical Performance Evaluation of the SysmexXR-20 analyzer with Sigma Metrics Eloisa Urrechaga, Eugenia Axpe, Andrea Nieto, Julen Madrazo, MA³nica FernAindez. Hospital Universitario Galdakao Usansolo, Galdakao, Spain

4:48

AI-driven high-throughput cytogenetics: enhancing diagnostic efficiency Isolde Summerer, Torsten Haferlach, Isabella Hartwig-Arnold, Dennis Bode, Nanditha Mallesh, Leroy Freyler, Sven Maschek, Christian Pohlkamp. Munich Leukemia Laboratory, MA¼nchen, Germany

4:00

Performance of one-stage and chromogenic FVIII assays in measuring efanesoctocog alfa activity: The impact of calibrator selection Sanne Vanthourenhout, Mohammad Amir, Katrien M.J. Devreese. Ghent university hospital, Ghent, Belgium

4:12

Reversal efficacy of novel single domain antibodies against rivaroxaban, edoxaban or apixaban in vitro and ex vivo: studying platelet-dependent clot formation under flow Xiang Gui1, 2, Bibian M.E. Tullemans1, Dionne C.W. Braeken2, Melanie J.de Jong2, Irme S. Franssen2, Fabienne J.H. Magdelijns3, Bas de Laat1, Hugo ten Cate1, 2, Johan W.M. Heemskerk1, Mark Roest1, Frauke Swieringa1. 1Synapse Research Institute, Maastricht, Netherlands.2Thrombosis Expert Centre, Maastricht University Medical Centre, Maastricht, Netherlands.3Department of General Internal Medicine, section of Geriatric Medicine, Maastricht University Medical Centre, Maastricht, Netherlands

4:24

Single Domain Antibodies to Reverse the Effects of Factor Xa Inhibitors in Coagulation Tests Ischa M.S. Hoornstra1, Junxiong Zhao1, 2, Dana Huskens1, Frauke Swieringa1, An K. Stroobants3, 4, Sanna Rijpma3, Bas de Laat1, Mark Roest1. 1Synapse Research Institute, Maastricht, Netherlands.2Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, Netherlands.3Department of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Nijmegen, Netherlands.4Department of Laboratory Medicine, Radboudumc Laboratory for Diagnostics, Radboudumc, Nijmegen, Netherlands

4:36

An accurate and pragmatic diagnostic algorithm for heparin-induced thrombocytopenia (HIT) in critically ill patients: an analysis of the TORADI-HIT study Henning Nilius1, Jan-Dirk Studt2, Dimitrios A. Tsakiris3, Bernhard Gerber4, Johanna A. Kremer Hovinga1, Tamam Bakchoul5, Michael Stickel1, Joerg C Schefold1, Michael Nagler1. 1Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.2University Hospital Zurich, Zurich, Switzerland.3Basel University Hospital, Basel, Switzerland.4Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.5University Hospital of TA¼bingen, TA¼bingen, Germany

4:48

Early Prediction of Thrombotic Thrombocytopenic Purpura from Routine Laboratory Data Using Machine Learning Ella Derkzen1, Jenyvette Hsia1, Benjamin Hedley2, Amy Tai2, 3, Michael Samuel2, Cyrus C. Hsia2, 4, Benjamin Chin-Yee2, 4. 1Faculty of Engineering, Western University, London, Ontario, London, ON, Canada.2Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.3Department of Computer Science, University of Waterloo, Waterloo, ON, Canada.4Division of Hematology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London Health Sciences Centre, London, ON, Canada

4:00

Flow Cytometry and Next-Generation Sequencing for MRD Detection in AML: Concordance Analysis and Genomic Characterization of Discordant Cases Aastha Gupta1, Rahul Bhargava1, Shrinidhi Nathany1, Nikita Chouudhary1, Surbhi Singh2, Rajul Bodkha2, Astha Shrivastava2, Anusha Swaminathan1, Priyanshi Pachauri3, Swati Bhayana1, Vikas Dua1. 1Fortis memorial research institute, Gurugram, India.2Agilus diagnostics, Gurugram, India.3Fortis Noida, Noida, India

4:12

Impact of Consanguinity on the Genetic Landscape of Beta-Thalassemia:Insights from a Five-Year Hospital-Based Cohort in Pakistan Zeeshan Ansar , Asghar Nasir , Muhammad Shariq Shaikh . Aga Khan University, Karachi, Pakistan

4:24

Machine Learning Application Using Local Haematology Analyzer Data (Mindray BC-760 & BC-6200) for Discriminating β-Thalassemia Trait and Iron Deficiency Tri Ratnaningsih1, Sri Ratna Fitriadewi2, Ciptaning Sari Dewi Kartika1. 1Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta Indonesia.2Duren Sawit General Hospital, Jakarta Indonesia

4:36

Emergency Ηematopoiesis: distinguishing the normal from the abnormal through proposed criteria using flow cytometry Angeliki Kotsiafti1, Christina Karela1, Georgios Oudatzis1, Maroula Milaiou1, Aikaterini Mandaraka1, Paraskevi Vasileiou2, Georgios Paterakis1. 1Department of Immunology, Athens General Hospital a, Athens, Greece.2AlFlowdiagnosisAr Diagnostic Center, Athens, Greece

4:48

Early Detection of Pre-Cytopenic Bone Marrow Failure Using Machine-Learned Complete Blood Count Ratios: A Multi-Institutional TriNetX Analysis Alaa Ramadan. Faculty of Medicine, South Valley University, Qena, Egypt

234

Evaluating Reticulocyte Hemoglobin for the detection of iron deficiency disorders in adults Isabel Aparicio-Calvente, Jennifer Rodriguez-Dominguez, Alba Leis-Sestayo, Laura Jimenez-AApon, Cristian Morales-Indiano, Alicia Martinez-Iribarren. Laboratory Medicine Department, Germans Trias i Pujol University Hospital, Badalona, Spain

235

Performances, reliability and ergonomics of a new hematology analyzer sthemA 601 evaluation N. Banh1, B. Butt1, C. Doinel1, L. Luquet1, V. Nadal1, T. Nguyen1, D. Paulin1, C. Ranaivoarimalala1, E. Geremia2, S. Melin2E. Tournier2, Dr. I. Habes Lenouar1, Dr. C. Brumpt1. 1Hematology laboratory, University Hospital LariboisiAure, Paris France.2Diagnostica Stago, AsniAures sur Seine France

236

Chronic Lymphoid Leukemia predictive model based on Complete Blood Count and Lymphocyte Positional Parameters performed in a Mindray®BC-6800 plus hematology analyzer Alfredo Bermejo Rodriguez1, Carmen Torres Gomez-Pimpollo2, Alejandro Bermejo Gordillo3. 1Hospital Universitario de Fuenlabrada, Fuenlabrada, Spain.2Universidad Rey Juan Carlos, Alcorcon, Spain.3Universidad Carlos III, Leganes, Spain

237

Comparative Analysis of Systemic Inflammation Response Index and Aggregate Index of Systemic Inflammation as Biomarkers of Low-Grade Inflammation in Polycystic Ovary Syndrome Natalia Dikova1, 2Milena Velizarova1, 2. 1Medical University, Dpt of Clinical Laboratory, Sofia Bulgaria.2University Hospital Alexandrovska, Sofia Bulgaria

238

Reference Interval Values of Monocyte Distribution Width among Healthy Adults: Age- and Sex-Related Variations Laura GarcAsa1, Sandra Ramos2, JesAos A. A2, Antonia M. Mayol1, Isabel AlbalAi1, Josu LA³pez2, Yael PAcrez2. 1Department of Laboratory Medicine, Hospital Juaneda Miramar, Palma de Mallorca, Spain.2Intensive Care Unit, Hospital Juaneda Miramar, Palma de Mallorca, Spain

239

Variations in detection of TP53 mutation by Immunohistochemistry in myeloid neoplasms Ismene Germanakos1, Dong Chen1, 2. 1University of Connecticut School of Medicine, Farmington, CT, USA.2University of Connecticut Health Center Department of Pathology and Laboratory Medicine, Farmington, CT, USA

240

Evaluation of Reference Interval For Extended Inflammatory Parameters (EIPs) Using Sysmex XN-10 Jia Hui Goh1, Ming Zi Soh1Shir Ying Lee1, 2. 1Department of Laboratory Medicine, Division of Haematology, National University Hospital, Singapore, Singapore.2Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore

241

Aiming for Precision Platelet Counting in Thrombocytopenia: An evaluation of platelet count by impedance methodology (PLT-I) and optical analysis (PLT-O) on HoribaTM 2500 vis-à-vis Digital Morphology platelet count (PLT-DM) on HoribaTMD20 Analyzer against reference method (PLT-R) in acute febrile illness with Platelet parameter flagging: An experience from a Tertiary Care Hospital Laboratory in India Anil Handoo1Prashant Nag2, Mudita Bhargava3, Ankur Lath4, Parul Babbar4, Paramjit Kaur4. 1BLK-Max Super Speciality Hospital, Pusa Road, New Delhi, India, New Delhi, India.2Tata 1mg Labs, Mumbai, India.3Max Super Speciality Hospital, Dwarka, New Delhi, India, New Delhi, India.4Horiba India Pvt Ltd, New Delhi, India

242

Comparison of differential count in leucopenic samples by the regular and low WBC mode on an automated hematology analyzer with the manual differential count. Shanaz KhodaijiMaitreyi Patwardhan, Vidisha Mahajan. P.D. Hinduja Hospital and Medical Research Centre, Mumbai, India

243

Evaluation of Total Vitamin B12 and Holotranscobalamin (active B12) as Diagnostic Markers of Vitamin B12 Deficiency Laura LAizaro1, Alba JimAcnez2, Alba Aljarilla2, Alejandro Aranda2, Marta Serra2, Marina Canyelles1, Javier Hernando-Redondo3, Nuria GonzAilez2Paula San-JosAc2. 1Biochemistry Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.2Hematology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.3Registre GironAs del Cor (REGICOR) Study Group, Hospital del Mar Research Institute (IMIM), Barcelona, Spain

244

Serial Extended Inflammation Parameter Monitoring Using a Composite Leukocyte Activation Model in Critically Ill Patients Noreen Louise1, Selina Gan2, Swee Jin Tan3, Suneta Sulaiman1. 1Institut Jantung Negara, Kuala Lumpur, Malaysia.2Sysmex Malaysia, Kuala Lumpur, Malaysia.3Sysmex Asia Pacific, Singapore, Singapore

245

Evaluation of general performances and the benefit of right-first-time analyses on sthemA 601 J. Mendes1, A. Pesson1, F. Leffray1, E. Letard1, M. Derbord1E. Tournier2, Dr. V. Cussac1, Dr. J. Rose1, Dr. C GuAcnot1. 1Hematology laboratory, Centre Hospitalier, Le Mans France.2Diagnostica Stago, AsniAures sur Seine France

246

Evaluation of novel Hybrid Platelet count (PLT-H) on BC-720 Mindray, Shenzhen analyzer and comparison with optical (PLT-O) and Impedance platelet (PLT-I) counting Aditi Mittal, Anil Handoo, Tina Dadu, Pratyush Mishra. Dept of Hematology, BLK-Max Super Speciality Hospital, Pusa Road, New Delhi, India

247

Screening for Chronic Myelomonocytic Leukemia in Automated Hematology Laboratories Using the Monocytosis Workflow Optimization (MWO) Application: A Multicenter Study Maida Navarrete1, Victor Navarro1, MarAsa JosAc Remigia 2, Paula Amat 2, Paula San JosAc3, Granada Perea 4, Elisabeth Gomez 5, Fiz Campoy5, Pablo Gonzalez 6, MarAsa Pilar JimAcnez 6, Jorge Medina 7, Carlos LAizaro 7, Carlos ChAivez8, Ana Sopena8Carlos Palacio1. 1Department of Hematology, Hospital Universitari Vall da, Barcelona, Spain.2Department of Hematology, Hospital ClAsnic Universitari, Valencia, Valencia, Spain.3Department of Hematology, Hospital de la Santa Creu i Sant Pau, Barcelona, Barcelona, Spain.4Department of Hematology, Parc TaulAs, Sabadell, Spain.5Department of Hematology, Complexo Hospitalario Universitario de Ourense, Ourense, Spain.6Department of Hematology, Hospital Universitario ClAsnico San Cecilio, Granada, Granada, Spain.7Department of Hematology, CATLAB, Barcelona, Terrasa.8Department of Hematology, Hospital Universitario Arnau de Vilanova, Lleida, Lleida, Spain

248

Defining Reference Intervals of Emerging Extended Inflammatory Parameters (EIP)in a Population-Based Study Karan Paisooksantivatana, Pawadee Chinudomwong, Atisak Jiaranaikulwanich, Mintra Tanakitivirul. Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

249

AI-Driven Identification of High-Value Samples: Multi-Modal Screening for Rare and Non-Typical Cases in Clinical Diagnostics. Cheng Qian, Ziling Huo. Dymuna Corp, Davie, FL, USA

250

Enhancing Hematology Malignancy Screening with Advanced Hematology Analyzers ChloAc Rampon1, Yan Liu2, Wendy Li2, Emilie Geremia2, Marc MaynadiAc1, Marie-Christine BenAc3, Julien Guy1. 1Biological Hematology department, Dijon University Hospital, Dijon France.2Mindray team, Shenzhen China.3Hematology, Nantes University, Nantes France

251

Screening for Malignancy Using Body Fluid Samples on Two Automated Hematology Analyzers: A Comparative Study Huaqing Shen, Xinjian CaiYiteng Lin. Cancer Hospital Chinese Academy of Medical Sciences Shenzhen Center, Shenzhen, China

252

First Uruguayan study using the Mindray CAL 8000-211: reference intervals for hematology and Research Use Only parameters in ambulatory adults (MUCAM, 2024–2025). Lucila I Silva1, Gabriela Chocho1, Miguel LujAin1, Ana K Ambsosetti1, Jimena Viera1, Gabriela Geymonat1, Marco Alpuin2, Macarena Acosta1, Mariela Luppi2, Cecilia Canessa1. 1Medica Uruguaya ( MUCAM), Montevideo Uruguay.2Biodiagnostico, Montevideo Uruguay

253

Performance Comparison of Automated Hematology Analyzers and Molecular Diagnostic Methods for Malaria Detection in Thailand Ekkaporn Sribunruang1, Pawinee Kutpatawintu2, Duangnapa Intharasongkroh3, Nipawan Yuttayoth3, Sathid Thessomboon2, Urassaya Pattanawong4, Chutitorn Ketloy1, Phandee Watanaboonyongcharoen1, 5. 1Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok Thailand.2National Blood Centre, Thai Red Cross Society, Bangkok Thailand.3Blood Testing Department, National Blood Centre, Thai Red Cross Society, Bangkok Thailand.4Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok Thailand.5Transfusion Medicine Unit, King Chulalongkorn Memorial Hospital, Bangkok Thailand

254

Establishment and validation of intelligent review rules for blood cell analysis based on the gradient boosting decision tree algorithm Wenjia Tang1, Shaoqian Chen2, Zhenglin Yu1, Xiumei Gu1, Baishen Pan1, Rong Ding3, Shihong Zhang2, Chong Wang1, Jing Lin4Xiaosen Bian5, Wei Guo1, Beili Wang1. 1Zhongshan Hospital, Fudan University, Shanghai China.2The First Affiliated Hospital of Sun Yat-sen University, Guangzhou China.3Southeast University Affiliated Zhongda Hospital, Nanjing China.4First People Hospital of Foshan, Foshan China.5Hematology Product Development Department, Shenzhen Mindray Bio-Medical Electronics Co. Ltd, Shenzhen China

255

Correlation of Monocyte Distribution Width with inflammation markers in systemic infection or sepsis Konstantina Tsioni1, Eftychia Nikolakopoulou2, Angeliki Karyoti1, Aikaterini Karantani1, Marianthi Issa1, Aristeidis Chalvantzis1, Dimitrios Komilis3Eleni Vagdatli1. 1Biopathology Laboratory, Hippokration General Hospital, Thessaloniki, Greece.2Biopathology Laboratory, Xanthi General Hospital, Xanthi, Xanthi, Greece.3Department of Environmental Engineering, Democritus University of Thrace, Xanthi, Greece

257

Comparison of complete blood count between K3-EDTA and MgSO4 samples AurAclie VAcdrenne1, Florence Habarou1, Tiffany Pascreau1, 2Marc Vasse1, 2. 1Biology Department, Foch Hospital, Suresnes France.2UMRS-1176, INSERM, Le Kremlin-BicAotre France

258

Development and validation of a complete blood count auto-verification model based on a large language model Di Wang1, Pengzhen Chen2, Jianping Xiao2, Xiaosen Bian2, Xiaomei Zhang2Haoqing Jiang1. 1Department of Laboratory Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai China.2Hematology Product Development Department, Shenzhen Mindray Bio-Medical Electronics Co. Ltd, Shenzhen China

259

Implementation of Digital Morphology Analyzer in Hematology Diagnostics: Evaluation of Workflow Efficiency and Diagnostic Accuracy Marina N. Zenina1, 3, Natalija Y. Chernysh2. 1Russian Research Institute of Hematology and Transfusiology Federal State Budgetary Institution of Higher Education, St.Petersburg, Russia.2Federal state budgetary institution, St.Petersburg, Russia.3North-Western State Medical University named after I.I. Mechnikov, St.Petersburg, Russia

260

Particle Point Cloud vs. Static Images from WBC Scattergrams: Performance in AI-Driven APL Screening Guoqing Zhu1, Min Xiao2, Zhangsong Yan1, Liyan Cui3. 1Institute of Hematology a Blood Diseases Hospital, Chinese Academy of Medical Sciences a Peking Union Medical College, Tianjin, China.2Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science a Technology, Wuhan, China.3Peking University Third Hospital, Beijing, China

261

A Novel IPF–Neutrophil Composite Score for Early Detection of Culture-Positive Sepsis: A High-Accuracy Clinical Tool Razan Hayati Zulkeflee1, 2, Rosline Hassan1, 2, Swee Jin Tan3, Ying Xian Lee3, Mohd Zulfakar Mazlan4, Sook Fong Ho5, Wan Nor Arifin 6. 1Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150 Kelantan, Malaysia.2Transfusion Medicine Unit, Hospital Universiti Sains Malaysia, Kubang Kerian 16150 Kelantan, Malaysia.3Sysmex Asia Pacific Pte Ltd., 528735, Singapore, Singapore.4Department of Anaesthesiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150 Kelantan, Malaysia.5Hospital Port Dickson, KM 11, Jalan Pantai, 71050 Sirusa Port Dickson, Negeri Sembilan, Malaysia.6Biostatistics and Research Methodology Unit, School of Medical Sciences, Universiti Sains Malaysia Kelantan, Malaysia

262

Lupus Anticoagulant-Hypoprothrombinemia Syndrome: Comparing Different Clinical Courses in Children and Adults Maryam Al-Saaidi1, Asma Al-Jahwari2, Murtadha Al-Khabori3, Maryam Al-Bakri3, Bader Al-Rawahi2, Nawal Al-Mashaikhi 4, Karima Al-Falahi2. 1Oman Medical Specialty Board, Muscat Oman.2Haematology Department, Sultan Qaboos University Hospital, University Medical City, Muscat Oman.3Haematology Department, College of Medicine and Health Sciences, Sultan Qaboos University, Muscst Oman.4Child Health Department, Sultan Qaboos University Hospital, University Medical City, Muscat Oman

264

Assessing the stability of routine coagulation assays in citrated plasma from healthy volunteers over a 24-hour period at room temperature using three different blood collection tubes. Lee Beckett1, Emma Broomhead1Jackie Dobson-Storr1, Anne Sermon-Cadd1, Kieron Hickey2. 1Laboratory Medicine, Department of Coagulation, Northern General Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.2Laboratory Medicine, Department of Coagulation, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom

265

Initial diagnosis of von Willebrand Disease in a 41-year-old woman with chronic iron deficiency Sofia K. Chaniotaki1, Eirini Manoli1, Anna Kalogianni1, Nikolaos J. Tsagarakis1, Ioulia Chaliori1, Charikleia Vlachou2, Anna Kouraba3, Dimitrios Liakopoulos1, Eleni Bortzari1, Maria Siarkou1, Christina Karela4, Stefanos J. Papadhimitriou1, Vasiliki Gountzouni1, Andria Yiaskouri1, Vasiliki Zina2Veroniki Komninaka1. 1Laboratory Haematology, a, Athens, Greece.2Haematology Clinic, a, Athens, Greece.3National Bleeding Disordersa, Athens, Greece.4Department of Laboratory Immunology, a, Athens, Greece

266

Method comparison of HemosIL Protein S Activity assay compared to CRYOcheck Clot S and HemosIL Free Protein S for the diagnosis of Protein S deficiency. Emily Erskine, Thomas Pitchford, Kieron Hickey. Haemostasis Department, South Yorkshire and Bassetlaw Pathology, AnAnRoyal Hallamshire Hospital, Sheffield, United Kingdom

267

Evaluation of the Enhanced HIL Function of the Sysmex Automated Blood Coagulation Analyser CN™-700: Precision Assessment and Comparative Analysis with the Sysmex Automated Blood Coagulation Analyser CN™-6000 Kevin Horner 1, Kerensa Leeson 1, Irfan Patel 2, Seigo Munehisa 3, Sakayori Tasuku 3, Matsuno Eriko3, Kieron Hickey1, Steve Kitchen1. 1Haemostasis Department, South Yorkshire and Bassetlaw Pathology, Royal Hallamshire Hospital, Sheffield, United Kingdom.2Sysmex UK Ltd, Milton Keynes, United Kingdom.3Sysmex Corporation, Kobe, Japan

268

Impact of In Vitro Activated Coagulation as a Pre-Analytical Error on Coagulation and Fibrinolysis Test Results Akiyo Kawamoto1, Eri Adachi1, Keisuke Nishi1, Takeshi Suzuki1, Nobuo Arai1, Hiroshi Kurono1, Kaho Kurashima2, 3, Itsuko Sato3, Tomoya Fukuoka3, 4, Ruri Kono2, 3, Kohei Morimoto2, Yoshinori Nakamura2, Yoshiharu Miyata2, 5, Takamitsu Imanishi3, Yoshihiko Yano3, Hiroshi Matsuoka2. 1Sysmex Corporation, Kobe, Hyogo, Japan.2Kobe University Hospital Bioresource Center, Kobe, Hyogo, Japan.3Department of Clinical Laboratory, Kobe University Hospital, Kobe, Hyogo, Japan.4Department of Clinical Laboratory Science, Tenri University, Tenri, Nara, Japan.5Department of Artificial Intelligence and Digital Health Science, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan

269

Performance evaluation of Revohem™ AT LRT reagent and improved on-board stability achieved with a new evaporationpreventing reagent rack Masafumi Kimura1, Kaori Otake1, Sho Shinohara2, Emeline Ronciere2, Claire Dunois2, Takeshi Suzuki1. 1Sysmex Corporation, Kobe Japan.2Hyphen BioMed, Neuville-sur-Oise France

270

Impact of Direct Factor Xa Inhibitors on Factor VIII Inhibitor Assays Piotr Kuta, Anne-Marie Breicher, Sarah Schultz, Thomas RennAc. Institute of Clinical Chemistry and Laboratory Medicine, Center for Diagnostics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

271

Development and Validation of a Hybrid AI Expert System for Coagulation Analysis: Integrating Rule-Based Logic with Generative AI for Intelligent Interpretation Guangjian Liu1, Lanli Zhang1, Tian Lin1, Tong Tian1Cheng Qian2, Ziling Huo2. 1Dymind Biotechnology Co., Ltd, Shenzhen, China.2Dymuna Corp, Davie, FL, USA

272

Comparison of Protein C Activity and Free Protein S Antigen Measured on the CS-2500 and BCS XP Coagulation Analyzers Marija Milic1, 2, Ksenija Paradinovic1, Jasna Stanfel3. 1Clinical Institute of Laboratory Diagnostics, University Hospital Centre Osijek, Osijek Croatia.2Faculty of Medicine Osijek, JJ Strossmayer University of Osijek, Osijek Croatia.3Medical-Biochemical Laboratory, Health Center for Osijek-Baranya County, Osijek Croatia

273

TEG Trends: A Closer Look at Ordering Patterns Valeria Moseley, Hazem Dahshan, Marc Anthony Pajarillo, Natalia Tarasova, Michelle Grant. Geisinger, Danville, PA, USA

274

Plasma Viscoelastic Characterization of COVID-Associated Coagulopathy in Pregnancy at Delivery and Postpartum Maha Othman1, 2, 3, Caroline Mwubaha1, 3, 4, Mustapha Alayan1, 3, 4, Maica Yunon3, 4, Sandra Blitz5, Deborah Money5, CANCOVID-Preg Team . 1Department of Biomedical and Molecular Sciences, Queena, Kingston, ON, Canada.2Clinical Pathology Department, Faculty of Medicine, Mansoura, Egypt.3School of Baccalaureate Nursing, St. Lawrence College, Kingston, ON, Canada.4Healthcare Administration Program, St Lawrence College, Kingston, Ontario, Canada, Kingston, ON, Canada.5Departments of Obstetrics and Gynecology, Medicine and the School of Population and Public Health, Faculty of Medicine, Vancouver, BC, Canada

275

Method Comparison of the Revohem Anti-Xa LRT assay Compared to Other Commercial Reagents – Monitoring of Xa-Direct oral anticoagulants Thomas Pitchford1, Kieron Hickey1, Steve Kitchen1, Tasuku Sakayori2, Miyu Kitagami2, Sho Shinohara3. 1Haemostasis Department, South Yorkshire and Bassetlaw Pathology, Royal Hallamshire Hospital, Sheffield, United Kingdom.2Sysmex Corporation, Kobe, Japan.3Hyphen BioMed, Neuville-sur-Oise, France

276

Verification of a chemiluminescent enzyme immunoassay for anti-heparin:platelet factor 4 antibodies using an automated haemostasis analyser Sean Platton1, 2, Jude Platton3, 4, Minal Dave3, 4, Anne Horton3, 4Katarzyna Kniola3, 4, Nada Yartey3, 4, Tadbir Bariana5. 1The Royal London Hospital Haemophilia Centre, London, United Kingdom.2Blizard Institute, Queen Mary University of London, London, United Kingdom.3Haemostasis Laboratory, Royal London Hospital, London, United Kingdom.4National Health Service East and South East London Pathology Partnership, London, United Kingdom.5Thrombosis and Haemostasis, Department of Haematology, Barts Health NHS Trust, London, United Kingdom

278

Preliminary analytical performance data of a new D-dimer assay Matthias Wilkens, Johanna Droese, Katja Woitaschek. Siemens Healthcare Diagnostics Products GmbH, Marburg, Germany

279

Correlation Study of Morphology, Immunophenotyping, and Mutation Landscapefor NPM1 Mutated Acute Myeloid Leukemia (AML) Norazlina Azman2, Yuslina Yosoff3, Joseph Tario1You-Wen Qian1. 1Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.2Tunku Azizah Hospital, Kuala Lumpur, Philippines.3Institute for Medical Research, Kuala Lumpur, Philippines

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Case report: Drug induced agranulocytosis treated with GCSF and delayed recovery mimicking an acute leukaemia Karen Alison Boyd1, 2. 1Western Diagnostic Pathology, Jandakot, Australia.2Joondalup Health Campus, Joondalup, Australia

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Diagnostic Utility of CD26 Expression on Circulating Leukemic Stem Cells as a Surrogate Marker in Chronic Myeloid Leukemia Gaurav Chhabra1, Shirin Sultana1, Somanath Padhi1, Ashutosh Panigrahi2. 1Department of Pathology a Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, India.2Department of Medical Oncology a Hematology, All India Institute of Medical Sciences, Bhubaneswar, India

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Automated B-cell and Plasma Cell Identification Using FlowSOM and a Transparent Excel Classifier Ethan Gantana1, 2, Ernest Musekwa1, 2, Erica-Mari Nell1, 2, Zivanai Chapanduka1, 2. 1Stellenbosch University, Cape Town, South Africa.2National Health Laboratory Service, Cape Town, South Africa

283

Fluorescence Activated Cell Sorting enhances molecular variant detection in newly diagnosed Acute Myeloid Leukemia Rodrigo Seiti Kojima, Luiz Gustavo Ferreira Cortes, Elizabeth Xisto Souto, Nair Hideko Muto, Roberta Cardoso Petroni, Laiz CamerApo Bento, Flavia Arandas de Sousa, Paulo Vidal Campregher, Joao Carlos de Campos Guerra, Nydia Strachman Bacal. Einstein Hospital Israelita, Sao Paulo, Brazil

284

Assessment of Platelet Function by Flow Cytometric Analysis: A Single-Centre Experience Kate Fung Shan Leung. Princess Margaret Hospital, Hong Kong, Hong Kong

285

Clonal Evolution and Lineage Switch to Mixed-Phenotype Acute Leukemia, B/myeloid in NUP98-rearranged AML Rachel Mariani1, 2. 1Phoenix Children's Hospital, Phoenix, AZ, USA.2University of Arizona College of Medicine Phoenix, Phoenix, AZ, USA

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COMPARING CONCORDANCE BETWEEN BD FACSLyricTM AND SYSMEX XF-1600TM INSTRUMENTS FOR EXPRESSION OF ACUTE LEUKEMIA SCREENING ANTIGENS Aditi Mittal1, Pradeep K Rai2, Tina Dadu1, Lekh Raj Mamania1, Jeffery Susilo3, Adam Winterhalter3Anil Handoo1. 1Dept of Hematology, BLK-Max Super Speciality Hospital, Pusa Road, New Delhi, India, New Delhi, India.2Sysmex India Pvt Ltd, Mumbai, India.3Sysmex Asia Pacific Pte Ltd, Singapore, Singapore

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Assay Value Assignment of Fresh Blood Calibrators for Leukocyte Differential Percentage with Evaluation of Their Convergence and Transport Stability - On behalf of The Japanese Society for Laboratory Hematology Standardization Committee (JSLH-SC) Sayaka Mori1, Tomohiro Takeda2, Yutaka Nagai2, 3, Yoko Yatabe4, Kazumichi Matsumoto5, Yoshinori Nishihara6, Kazuto Tsuruda1, Tohru Inaba7, Kei Shimbo8, Katsunori Yanagihara1, 9, Hiromichi Matsushita3, Akiyoshi Takami10. 1Nagasaki University Hospital, Nagasaki, Japan.2Kansai University of Health Sciences, Osaka, Japan.3Keio University School of Medicine, Tokyo, Japan.4Keio University Hospital, Tokyo, Japan.5Kyoto Prefectural University of Medicine Hospital, Kyoto, Japan.6Sysmex Corporation, Kobe, Japan.7Kyoto Prefectural University of Medicine, Kyoto, Japan.8Dokkyo Medical University Hospital, Tochigi, Japan.9Nagasakiken Medical Association, Nagasaki, Japan.10Aichi Medical University, Nagakute, Japan

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Utility of Flow Cytometric PAX5 Protein Detection for the Diagnosis of B-cell Acute Lymphoblastic Leukemia Karan Paisooksantivatana2, Tanintorn Pootrakul1, Burana Khiankaew1, Paisarn Boonsakan1. 1Saraburi Hospital, Saraburi, Thailand.2Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Use of flow cytometry in the diagnosis of paroxysmal nocturnal hemoglobinuria Masa Sladojevic1, 3, Stanislava Nikolic1, 3, Tanja Sasic Ostojic1, 3, Dusan Sedlarevic1, 3, Amir El Farra2, 3, Velibor Cabarkapa1, 3. 1Center of Laboratory Diagnostics, University Clinical center of Vojvodina, Serbia, Novi Sad Serbia.2Clinic of Hematology, University Clinical center of Vojvodina, Serbia, Novi Sad Serbia.3Faculty of Medicine, University of Novi Sad, Serbia, Novi Sad Serbia

291

Molecular Identification and Characterization of Uncommon Breakpoint Cluster Region–Abelson Transcripts in a Tertiary Reference Laboratory in Pakistan Zeeshan Ansar , Asghar Nasir , Muhammad Shariq Shaikh . Aga Khan University, Karachi Pakistan

292

Strong As Well As Null p53 Immunohistochemical Staining Predicts TP53 Mutation In Haematological Neoplasms. Richa Chauhan, Meghna Yadav, Jasmita Dass, Ganesh Kumar Vishwanathan, Mukul Aggarwal, Rishi Dhawan, Pradeep Kumar, Tulika Seth, Manoranjan Mahapatra. Department of Haematology, All India Institute of Medical Sciences, New Delhi, India

293

Ultra-sensitive molecular MRD on flow cytometer using superRCA mutation assay Irene Golan, Shirin Khaliliazar, Tomas EdgrenLei Chen. Rarity Bioscience AB, Uppsala, Sweden

294

Comparison of Digital and Conventional Real-Time Quantitative PCR for BCR::ABL1 Monitoring in Chronic Myeloid Leukemia Patients Jin-Yeong Han1, 2, Suji Park1, Jae-Ryong Shim1. 1Department of Laboratory Medicine, Dong-A University College of Medicine, Busan, South Korea.2Seegene Medical Foundation, Busan, South Korea

295

Spectrum and clinical impact of hotspot mutations in acute myeloid leukaemia (AML) detected by targeted next-generation sequencing (NGS): experience from a resource-limited setting Wajeeha Iftikhar, Zeeshan Ansar, Usman Shaikh, Bushra Moiz. AGA KHAN UNIVERSITY HOSPITAL, Karachi, Pakistan

296

Optical Genome Mapping as a promising tool for identification of less frequent translocations in multiple myeloma Jana Kotaskova1, 2, Andrea Mareckova1, Eva Ondrouskova1, Michaela Bilcikova1, Johana Mayerova1, Tereza Ruzickova1, 3, Jakub Pavel Porc2, 4, Tomas Reigl2, 4, Veronika Navrkalova1, 2, 4, Nela Sendlerova1, Martin Stork1, Ludek Pour1, Sabina Sevcikova1, 3, Marie Jarosova1, 2. 1Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic.2Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University, Brno, Czech Republic.3Babak Myeloma Group, Department of Pathophysiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.4Central European Institute of Technology, Masaryk University, Brno, Czech Republic

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Concurrent MYC and CCND1 aberrations define an aggressive subtype of B-cell neoplasm with atypical diagnostic features Dimitrios Liakopoulos1, Stefanos I. Papadhimitriou1, Dimitrios Pavlidis1, Nikolaos J. Tsagarakis1, Ioulia Chaliori1, Sofia Chaniotaki1, Eirini Manoli1, Anna Kalogianni1, Christina Karela2, Andria Yiaskouri2, Stavros Kalafatis1, Athanasios Alexopoulos1, Evi Farmaki1, Georgios Paterakis2Veroniki Komninaka1. 1Hematology Laboratory, GNA a, Athens, Greece.2Department of Immunology, GNA a, Athens, Greece

298

Spectrum and Frequency of TP53 Alterations in Multiple Myeloma: A Single-Center Experience Johana Mayerova1, Tereza Ruzickova1, 2, Andrea Mareckova1, Eva Ondrouskova1, Michaela Bilcikova1, Viera Hrabcakova1, Marek Borsky1, Sarka Pavlova1, 3, 4, Martin Stork1, Sabina Sevcikova2, Ludek Pour1, Marie Jarosova1, 4, Jana Kotaskova1, 4. 1Center of Molecular Biology and Genetics, Department of Internal Medicine, Hematology and Oncology, University Hospital Brno, Brno, Czech Republic.2Babak Myeloma Group, Department of Pathophysiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.3Central European Institute of Technology, Masaryk University, Brno, Czech Republic.4Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University, Brno, Czech Republic

299

Impact of Somatic Mutations on Treatment Response and Resistance in Chronic Myeloid Leukemia Shruti Mishra1, Kailash Kumar2, Dinesh Kumar2, Ashwin Kamak2, Lovely Singh2, Nilesh Kumar2. 1Bone Marrow Transplantation and Stem Cell Research Centre, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.2Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

300

Uncovering Complex Structural Alterations in Waldenström Macroglobulinemia Using Optical Genome Mapping Tereza Ruzickova1, 2, Johana Mayerova2, Andrea Mareckova2, Viera Sandecka2, Marie Jarosova2, 3, 4, Sabina Sevcikova1, Jana Kotaskova2, 4. 1Babak Myeloma Group, Department of Pathophysiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.2Department of Internal Medicine, Hematology and Oncology, University Hospital Brno, Brno, Czech Republic.3Central European Institute of Technology, Masaryk University, Brno, Czech Republic.4Institute of Medical Genetics and Genomics, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic

301

Factors Associated With Positive Cerebrospinal Fluid mNGS Results and Development of a Predictive Model in Patients With Suspected Viral Meningitis Chengfeng Shu. Bishan Hospital of Chongqing medical university, Bishan Hospital of Chongqing, Chongqing, ID, China

302

FNDC3B as a Novel NPM1c-Menin Target Predicts Favorable Prognosis and Immunotherapy Response Across Hematological Malignancies Zijun Xu, Wanzhu Liu, Tingxin Gao, Haoyu Cao, Fei Wang, Xiangmei Wen, Wei Zhao, Jiang Lin, Jun Qian. Affiliated Peoplea, Zhenjiang, China

303

Unmasking Acute Leukemia: When Malaria Confounds Diagnosis—A Case Report Hanin B. Al Douhani1, Maryam S. Al Bakri2, Thuraya K. Al-busa'idi2, Abdelhadi M. Shebl2. 1Oman Medical Speciality Board, Muscat, Oman.2Sultan Taboos University Hospital, Muscat, Oman.3Sultan Taboos University Hospital, Muscat, Oman.4Sultan Taboos University Hospital, Muscat, Oman

304

Recognition of myelodysplastic syndrome and chronic myelomonocytic leukemia using the Sysmex XR analyzer score Alex BarragAin MuApoz, Angel Molina , JosAc Luis Bedini, Anna Merino. CORE Laboratory. Biochemistry and Molecular Genetics Department. Biomedical Diagnostic Center. Hospital Clinic. Barcelona. Spain, Barcelona, Spain

305

Discrimination of malaria parasites from other red blood cell inclusions using a SAM-ConvNeXt-based AI model Kevin Barrera2, Mireia GarcAsa4, A Molina1, JosAc Rodellar3, Anna Merino1. 1CORE Laboratory. Biochemistry and Molecular Genetics Department. Biomedical Diagnostic Center. Hospital Clinic, Barcelona, Spain.2Control, Data and Artificial Intelligence (CoDAlab), Department of Mechanical Engineering, Escola da, Barcelona, Spain.3Control, Data and Artificial Intelligence (CoDAlab), Department of Mathematics, Escola da, Barcelona, Spain.4Bioinformatics and Biostatistics, Universitat Oberta de Catalunya (UOC), Barcelona, Spain

306

Deep Learning Quantification of Reactive Lymphocytes in Peripheral Blood Predicts Clinical Outcome After CAR-T Therapy Alejandro Calvera1, Kevin Barrera2, Jose Rodellar2, Nuria MartAsnez-CibriAin3, Nil Albiol3, Aina Oliver3, Julio Delgado3, Carlos FernAindez de Larrea3, ValentAsn Ortiz-Maldonado3, Anna Merino4. 1Biochemistry and Molecular Genetics Department, Biomedical Diagnostic Center (CDB), Hospital ClAsnic of Barcelona, Barcelona, Spain.2Mechanical Engineering Department, Universitat PolitAucnica de Catalunya - BarcelonaTech, Barcelona, Spain.3Hematology Department, Hospital ClAsnic of Barcelona, Barcelona, Spain.4CORE Laboratory, Biomedical Diagnostic Center (CDB), Hospital ClAsnic of Barcelona, Barcelona, Spain

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POINT-OF-CARE WHITE BLOOD CELL DIFFERENTIAL TESTING IN PEDIATRIC INPATIENTS (2 MONTHS-17 YEARS): ANALYTICAL AND DIAGNOSTIC PERFORMANCE OF HEMOSCREEN Alessio Correani1, 2, Beatrice Niccoletti3, Marianna Pavani3, Michela Sampaolo3, Lucia Finaurini3, Michela Pelloso4, Martina Montagnana4, 5, Marco Moretti3. 1University of Padua, Department of Biomedical Sciences, Padua, Italy.2UniversitAn Politecnica delle Marche, Department of Odontostomatologic and Specialized Clinical Sciences, Ancona, Italy.3Medicina di Laboratorio, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy.4Laboratory Medicine, University-Hospital of Padua, Padua, Italy.5University of Padua, Department of Medicine, Padua, Italy

308

Red blood cell rods: A hitherto undescribed morphologic finding Katherine A. Devitt1, 2, Juli-Anne Gardner1, 2, Clayton Wilburn1, 2, Pamela C. Gibson1, 2, Russell W. Brown1, Brad P. Vietje2, Douglas J. Taatjes2. 1University of Vermont Medical Center, Burlington, VT, USA.2Larner College of Medicine at the University of Vermont, Burlington, VT, USA

309

A Multicentre Pivotal Clinical Study of ASUS Blade: Artificial Intelligence for Peripheral Blood Film Analysis Bingwen Eugene Fan1, 2, 3, 4, David Tao Yi Chen5Wei Yong Kevin Wong6, Kian Guan Eric Lim6, Yi Xiong Ong6, Cathy Chang5, Pik Wan Erica Chiang1, Yu Yue Hew1, Siti Thuraiya Binte Abdul Latiff2, Chiew Yan Lee1, Sanchalika Acharyya7, Rui Yuan Shum5, Moh Sim Wong2, Hemalatha Shanmugam1, Stefan Winkler5, Ponnudurai Kuperan1, 2, 3, 4. 1Department of Haematology, Tan Tock Seng Hospital, Singapore, Singapore.2Department of Laboratory Medicine, Khoo Teck Puat Hospital, Singapore, Singapore.3Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.4Yong Loo Lin School of Medicine, National University of SIngapore, Singapore, Singapore.5ASUS Global Pte Ltd, Singapore, Singapore.6Department of Laboratory Medicine, Tan Tock Seng Hospital, Singapore, Singapore.7Clinical Research and Innovation Office, Tan Tock Seng Hospital, Singapore, Singapore, Singapore

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Detection and Classification of Megakaryocyte Dysplasia Using Deep Learning Defne Gulmez1, Elif G Umit2. 1Sorbonne UniversitAc, Department of Engineering and Computer Science, Paris France.2Trakya University School of Medicine, Department of Hematology, Edirne Turkey

311

Blast morphological abnormalities in de novo acute myeloid leukemia (excluding acute promyelocytic leukemia) and their associations with genetic alterations. Ajeeva Ithayakumar, Eric Guiheneuf. CHU Amiens-Picardie, Amiens, France

312

Blind Diagnostician Language: A multimodal system for structured analysis of medical image data with application in haematological cytomorphology Milos Kudelka1David Starostka2, Tomas Anlauf1, Lukas Papik1, Richard Dolezilek3. 1Department of Computer Science, Faculty of Electrical Engineering and Computer Science, Technical University of Ostrava, Ostrava, Czech Republic.2Laboratory of Haematooncology and Clinical Biochemistry, Hospital Havirov, Havirov, Czech Republic.3Department of Pathology, Hospital Havirov, Havirov, Czech Republic

313

Development of a Convolutional Neural Network Model for Automated Pre-classification of Bone Marrow Cells Junxun Li1, Haiquan Chen2, JianPing Xiao2, Yuan Xing2, Shan Yu2, Yan Liu2, Bo Ye2. 1The First Affiliated Hospital, Sun Yat-sen University, Guangzhou China.2Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd, Shenzhen China

314

Serial peripheral blood morphologic monitoring of CAR-T cell expansion and biological activity John D Marra1, 2, Simona Sica1, 2, Federica Sora'1, 2, Eugenio Galli1, 2, Ilaria Pansini1, 2, Alessandro Corrente1, Silvia Bellesi2, Nicoletta Pelliccioni2, Gina Zini1, Patrizia Chiusolo1, 2. 1Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, UniversitAn Cattolica del Sacro Cuore, Rome, Italy.2Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario a, Rome, Italy

315

Comparative evaluation of blast detection in acute leukemia by the Mindray MC-80 digital microscope versus manual microscopy Dyna M. Medetova, Daria D. Kovaleva, Vladimir S. Vlasov, Yulia V. Mirolyubova, Yulia I. Karpova, Natalia Y. Chernysh, Elena Y. Vasilyeva. Federal state budgetary institution, St.Petersburg, Russia

316

Performance of the AI-Based Digital Morphology Analyzer (CAL6000, Mindray) for Peripheral Blood Leukocyte Differential from Donor Samples Margarita E. Pochtar1, 2, Svetlana A. Lugovskaya1, 2, Nadezhda S. Markina1, Evgeniy V. Pochtar1, Alexander I. Kostin3, Ludmila A. Romanova1. 1Russian Medical Academy of Continuing Professional Education, Ministry of Health of the Russian Federtion, Moscow, Russia.2Botkin Hospital, Moscow, Russia.3Sklifosovsky Research Institute for Emergency Medicine, Moscow Department of Health, Moscow, Russia

317

Body Fluid Cell Differentiation: A Comparison Between CellaVision DI-60 and Manual Microscopy in Pleural and Ascitic Fluids Paula San-JosAc1, Alba Aljarilla1, Alba JimAcnez1, Nuria GonzAilez1, Javier Hernando-Redondo2, Josep F. NomdedAcu-Guinot1. 1Hematology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.2Registre GironAs del Cor (REGICOR) Study Group, Hospital del Mar Research Institute (IMIM), Barcelona, Spain

318

Reference Range for the Automated Fragmented Red Cell Parameter and Its Diagnostic Utility in Red Blood Cell (RBC) Fragment Quantification: A Prospective Study Tushar Sehgal1, Ginni Bharti1, Hemchandra Pandey2, Hem Sati3. 1Department of Laboratory Medicine, AIIMS, New Delhi, India.2Department of Transfusion Medicine, AIIMS, New Delhi, India.3Department of Biostatistics AIIMS, New Delhi, India

319

Internuclear Bridging in Neutrophils: A Previously Undescribed Morphologic Finding Elizabeth Tingey, David M. Conrad. Department of Pathology, Dalhousie University, Halifax, NS, Canada

320

HemoPulse: Interpretable Deep Learning of Peripheral Blood Morphology for Monitoring Acute Deterioration in Hospitalized Cancer Patients Dylan C. Webb1, 2, Cesar Colorado-Jimenez1, Maly Fenelus1, Zhanghan Yin1, 2, K. Hasan Bilal1, A. Zara Herskovits1, Deepika Dilip1, 3, Tiffanny Newman4, Shenghuan Sun5, Linlin Wang6, Mikhail Roshal1, Lauren McVoy1, Oscar BrA¼ck7, 8, 9, Ahmet Dogan1, Chad Vanderbilt1, Gregory M. Goldgof1. 1Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.2Department of Statistics, University of California-Berkeley, Berkeley, CA, USA.3School of Medicine, New York Medical College, Valhalla, NY, USA.4Department of Strategy and Growth, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.5Bakar Computational Health Sciences Institute, University of California-San Francisco, San Francisco, CA, USA.6Department of Laboratory Medicine, University of California-San Francisco, San Francisco, CA, USA.7Department of Oncology, University of Helsinki, Helsinki, Finland.8Hematoscope Lab, Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland.9Department of Clinical Chemistry, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

321

Erythrocytes sedimentation rate assessment using Mindray BC-760 vs. gold standard Westergren method: A comparative study Malgorzata Wituska1, Szczepan Wasik2Olga Ciepiela1, 3. 1Central Laboratory, University Clnical Center of Medical University of Warsaw, Warsaw, Poland.2Students Scientific Group of Laboratory Medicine, Medical University of Warsaw, Warsaw, Poland.3Department of Laboratory Medicine, Medical University of Warsaw, Warsaw, Poland

322

Toll-Like Receptor Gene Polymorphisms in Immune Thrombocytopenia: Implications for Disease Mechanism and Clinical Presentation Nurul Izzah Abdul RazakNoor Haslina Mohd Noor, Muhammad Aidil Zahidin, Hisham Atan Edinur, Nur Ilyia Syazwani Saidin. Department of Hematology, Health Campus, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, ME, Malaysia

323

Targeting BTK Protein in Platelets with PROTAC (DD 03-171): A Novel Approach for Cardiovascular Disease Management Afnan F Alhammadi, Amelia Drysdale, Bismah Mateen, Sarah Jones. Manchester Metropolitan University, Manchester, United Kingdom

324

Beyond Hemostasis; Platelets at the Crossroads of Immunity and Thrombosis: Comparative Analysis of Arboviral NS1-Mediated Activation Alan F Cano-Mendez, Nallely I Garcia-Larragoiti, Patricia Guzman-Cansino, Laura-Gabriela Flores-Avina, Carolina Chiaroni-Score, Thomas Klifopoulus Martha-Eva Viveros-Sandoval. Laboratorio de Hemostasia y BiologAsa Vascular Ignacio Chavez School of Medicine, UMSNH, Morelia, Mexico

325

Machine Learning-Driven Identification of a Multi-gene Tumor-Educated Platelet RNA Signature for the Accurate Diagnosis of Pancreatic Cancer Eunhui Ji1, Seung Hwan Oh1, 2, In-Suk Kim1, 2. 1Department of Laboratory Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.2Department of Laboratory Medicine, Pusan National University School of Medicine, Yangsan, Korea

326

Performance characteristics of various platelet detection technologies between XN-20 and BC-6800 Plus Ji Hyun Kim, Douglas Lim, Yuki Ong, Nurul Khaleeda Mulok, Chuen Wen Tan. Singapore General Hospital, Singapore, Singapore

327

Platelet activation and platelet–leukocyte conjugates in magnesium sulphate anticoagulated blood Steffen MannuA1, 2, Oliver Tiebel3, Peter Schuff-Werner1. 1Rostock University Medical Center, Institute of Clinical Chemistry and Laboratory Medicine, Rostock, Germany.2Ludwigshafen City Hospital, Institute of Laboratory Diagnostics, Hygiene and Transfusion Medicine, Ludwigshafen, Germany.3Technical University Dresden Klinikum a, Dresden, Germany

328

Beyond Immunity and Heart Defects: Platelet Marker Expression as a Window into DiGeorge Syndrome Priyanka Pandey1, Michele Paessler1, 2. 1Department of Pathology and Laboratory Medicine, Childrena, Philadelphia, PA, USA.2Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

329

Correlation between chronolog and automated coagulation analyser results for platelet aggregation test. Maryam Pourabdollah. university of Ottawa, ottawa, ON, Canada

330

Clinical Utility of Optical Fluorescent Platelet Counting Using the BC-6200 Hematology Analyzer in EDTA-Dependent Pseudothrombocytopenia. MaA Wituska1, Olga Ciepiela2. 1Central Laboratory, University Clinical Center of Medical University of Warsaw, Warsaw, Poland.2Department of Laboratory Medicine, Medical University of Warsaw, Warsaw, Poland

331

Molecular Characterization of Borderline High Hemoglobin A in Oman: Implications in β-Thalassemia Carrier Detection Noor Al-Balushi1, Buthaina Al-Maashari2, Arwa Al-Muharrami3. 1Hematopathology residency program, Oman Medical Specialty Board, Muscat Oman.2Department of Hematology, Royal Hospital, Ministry of Health, Muscat Oman.3General Foundation Program, Oman Medical Specialty Board, Muscat Oman

332

Population Distributions of Reticulocyte Hemoglobin and Immature Reticulocyte Fraction in Inpatient and Outpatient Adults at a Tertiary Hospital Tar Choon Aw1, Noor Ashraf Ardeefia Kamaludin1, Hillyah Mohd Zulkifli1, Swee Jin Tan2. 1Department of Laboratory Medicine, Changi General Hospital, Singapore, Singapore.2Sysmex Asia Pacific, Singapore, Singapore

333

Preliminary Evaluation of the “Reticulocytosis” Alert Generated by the Mindray BC-7800 DIFF Channel: Analytical Performance and Clinical Significance Vincenzo De Iuliis, Mario Forcella, Cristina Di Saverio, Giusy BoveSofia Chiatamone Ranieri. Department of Clinical Pathology, G. Mazzini Civil Hospital, Teramo, Italy

334

Lipid Interference Flagging and Hemoglobin Correction in Hyperlipidemia Samples with a Hematology Analyzer Yinhua Fan1, Yimin Shen1, Dongmei Liu1, Yong Wang1, Jun Cao1, Bo Zhao1, Yushuai Ma2, Zijie Chen2, Yan Liu2, Shuaishuai Zhang1. 1Department of Laboratory Medicine, The First Affiliated Hospital of Suzhou University, Suzhou China.2Department of Clinical Research a Medical Affairs, Shenzhen Mindray Bio-Medical Electronic Co., Ltd., Shenzhen China

335

The futility of Hemoglobin H preparation in diagnosing Alpha Thalassemia trait. A two-year retrospective study. Anwar Hajiya, Brittany Armitage, Kyla NorrisEileen R McBride. Children's Hospital of Eastern Ontario, Ottawa, ON, Canada

336

Prevalence and specificity of irregular red blood cell antibodies in pregnant women attended at a reference hospital in Catalonia Alba Leis-Sestayo, Jennifer RodrAsguez-DomAsnguezIsabel Aparicio-Calvente, Laura JimAcnez-AApA³n, Cristian Morales-Indiano, Alicia MartAsnez-Iribarren. Laboratory Medicine Department, Germans Trias i Pujol University Hospital, Badalona, Spain

337

Newborn Screening Pitfalls in Hemoglobin C Disorders: Compound Heterozygosity with Hemoglobin Lepore and Hereditary Persistance of Fetal Hemoglobin Christopher Liwski1, Andrea Rideout2, Corey Filiaggi3, 4, David M. Conrad1, 3. 1Department of Pathology, Nova Scotia Health, Halifax, NS, Canada.2Maritime Medical Genetics Service, IWK Health, Halifax, NS, Canada.3Department of Pathology and Laboratory Medicine, IWK Health, Halifax, NS, Canada.4Maritime Newborn Screening, IWK Health, Halifax, NS, Canada

338

Haptoglobin is not a helpful marker of hemolysis in children. Eileen R McBride1, Jason C Ford2. 1Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.2Sidra Medicine, Doha, Qatar

339

Epidemiology and Immunohematological Characteristics of Autoimmune Haemolytic Anaemia in a Malaysian Tertiary Hospital: A Two-Year Retrospective Study noor haslina mohd noor, noor shafika galtani, nurul izzah abdul razak, salfarina iberahim, marini ramli, zefarina zulkafli, mohd nazri hassan, shafini mohamed yusof. haematology department, universiti sains malaysia, KUBANG KERIAN Malaysia

340

Next Generation Sequencing as a Diagnostic Tool for Comprehensive Haemoglobinopathy Genotyping: A Validation Study Norafiza binti mohd Yasin1, Nurul Hidayah binti musa1, Faidatul Syazlin binti Abdul Hamid1, Syahzuwan bin Hassan1, Suguna A/P Somasundram1, Azian Naila Md Nor1, Ermi Neiza Mohd Sahid1, Yuslina binti Mat Yusoff 1, Ezzanie Suffya Zulkefli1, Ezalia Esa2. 1Haematology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), National Institute for Health (NIH), Setia Alam, Malaysia.22Virology Unit, Infectious Disease Research Center, Institute for Medical Research, National Institute for Health (NIH), Setia Alam, Malaysia

341

Genotype-Based Prediction of Response to Thalidomide as a Fetal Hemoglobin Augmentation Agent in Transfusion-Dependent Beta-Thalassemia IRAM NAZIR1, 2, Muhammad Younus Jamal Siddiqi2, 3, Maeesa Wadood2, Muhammad Rizwan2. 1Amna Inayat Medical College, Lahore, Pakistan, Lahore Pakistan.2Baqai Institute of Hematology, Baqai Medical University, Karachi, Pakistan, Karachi Pakistan.3Jinnah Medical a Dental College Karachi, Karachi Pakistan

342

Observations from External Quality Assessment: G6PD Quantitative Assay vs Qualitative Screening Bianca Olivier, Bashori Rahman, Barbara De La Salle, Joana Loureiro. UK NEQAS Haematology, Hertfordshire, United Kingdom

343

Testing for hemoglobinopathies in an emergency setting: a quality improvement study Yves D. Pastore1, 2, Maria Tamer1, Nasa Allaoui3, Kim-Lien Ho1, Leila Rabaamad2, Evelyne Doyon-Trottier4, Sebastien B. Lavoie2, 5, Tiago Nava1, 2, 6. 1Pediatric hematology section, pediatric department, CHU Sainte-Justine, MONTREAL, QC, Canada.2Clinical department of laboratory medicine, CHU Sainte-Justine, MONTREAL, QC, Canada.3Ethic, performance and quality department, CHU Sainte-Justine, MONTREAL, QC, Canada.4Pediatric emergency department, CHU Sainte-Justine, MONTREAL, QC, Canada.5Biochemistry service, clinical department of laboratory medicine, CHU Sainte-Justine, MONTREAL, QC, Canada.6Pharmacology research unit, clinical department of laboratory medicine, CHU Sainte-Justine, MONTREAL, QC, Canada

344

Diagnostic Performance Of Extended Red Cell Parameters In Iron Deficiency Anaemia Among Young Children Marini Ramli1, 2, Fatma Basyira Jamallodin1, 2, Wan Suriana Wan Abdul Rahman2, NurIlyia Syazwani Saidin1, 2. 1School Of Medical Sciences, University Sains Malaysia, Kota Bharu, Kelantan Malaysia.2Hospital Pakar Universiti Sains Malaysia, Kota Bharu, Kelantan Malaysia

345

Does the Ferroportin 1 −8C>G Variant Modify Iron Overload and Iron Regulatory Biomarkers in Transfusion-Dependent Beta Thalassemia Patients Receiving Hemoglobin F Augmentation Therapy? Maeesa Wadood1, 2, Muhammad Younus Jamal Siddiqui1.3, Iram Nazir1.4, Syeda Ayesha Siddiqa2, Mazahir Hussain2, Muhammad Rizwan1, Munazza Rashid1, Maria Rahim1. 1Baqai Medical University, Karachi Pakistan.2Muhammadi Hematology, Oncology Services and Welfare Foundation, Karachi Pakistan.3Jinnah Medical a Dental College, Karachi Pakistan.4Amna Inayat Medical College, Lahore Pakistan

346

Defining Population-Specific G6PD Activity Thresholds Using a Stable Adjusted Male Median: Evidence from 16 Years of Nationwide Data Muhammad Shariq Shaikh, Zeeshan Ansar Ahmed, Bushra Moiz. Aga Khan University Hospital, Karachi, Pakistan

348

Glycemic Control and Systemic inflammation: Exploring the Correlation between HbA1c, HOMA-IR and Procalcitonin. A preliminary report Konstantina Tsioni1, Eftychia Nikolakopoulou2, Nikoletta M Kouri1, Angeliki Karyoti1, Marianthi Issa1, Aristeidis Chalvantzis1, Dimitrios Komilis3Eleni Vagdatli1. 1Biopathology Laboratory, Hippokration General Hospital, Thessaloniki, Greece.2Biopathology Laboratory, Xanthi General Hospital, Xanthi, Xanthi, Greece.3Department of Environmental Engineering, Democritus University of Thrace, Xanthi, Greece

349

Interference in MCHC measurement: experience in our laboratory in analyzing causes and management with the help of CBCO-Sysmex software Teresa M Villalba Hernandez1, Maria Gonzalez Boronat1, Miquel Diaz Valls1, 2, Jorge Y Medina Ugarelli1. 1Catlab laboratoris, Terrassa, Spain.2Hospital Universitari Mutua de Terrassa, Terrassa, Spain

350

Advanced Algorithm for Correcting Cold Agglutination Interference in Red Blood Cell Parameters with the Mindray BC-7600 Hematology Analyzer Bo Ye1, Jong Zhang2, Wenbo Zheng1, Danzhou Tao1, Zhongfu Zhang1, Yushuai Ma1, Yan Liu1, Taiqiang Zhao2. 1Department of Clinical Research a Medical Affairs, Shenzhen Mindray Bio-Medical Electronic Co. Ltd., Shenzhen China.2Department of Laboratory Medicine, Sichuan Academy of Medical Sciences a Sichuan Provincial Peoplea, Chengdu China

351

Worst-Case Hyperhemolysis Syndrome: Massive Hemorrhage Protocol Activation After Splenectomy Sima Zolfaghari1, Hafsah Ibrahim Chalchal1, Jennifer Lambert2. 1University of Saskatchewan, Regina, SK, Canada.2Regina General Hospital, Regina, SK, Canada

352

InHospital Value Assignment for Repurposing Reference Materials for WithinLaboratory Precision as Trueness Control Materials Using Six FreshBloodVerified Hematology Analyzers to Enable ReferenceMaterialDriftIndependent Daily Sequential Calibration Verification Tomoko Arai1Yutaka Nagai2, 3, Yoko Yatabe1, Hiromichi Matsushita1, 2. 1Keio University Hospital, Tokyo, Japan.2Keio University School of Medicine, Tokyo, Japan.3Kansai University of Health Sciences, Osaka, Japan

353

Extending accurate patient-based quality assurance and quality control to outpatient (referral) laboratory testing George Cembrowski1, Jialin Qiu2, Christopher McCudden3. 1Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.2University of Alberta, Edmonton, AB, Canada.3University of Ottawa, Ottawa, ON, Canada

354

Analytical Validation of the Atellica HEMA 580 Hematology Analyzer and Comparative Performance Against the Sysmex XN Melwin Deepak, Amira Al Mawali, Mariam Al Buraiki, Shaima Al MamariMohamed Al Zaabi MD, FRCPath. Department of Hematology Laboratory and Blood Bank, Khoula Hospital, Muscat Oman

356

Raising Awareness of Emerging Pathogens through Morphology Proficiency Testing Anna Johnston1, Alex Kumaritakis1, Tess Koerner2, Antoine Corbeil3, David Good4. 1Institute for Quality Management In Healthcare, Toronto, ON, Canada.2Accreditation Canada, Ottawa, ON, Canada.3Public Health Ontario, Toronto, ON, Canada.4Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada

357

The Pitfall of Relying on Manufacturer-Assigned MNPT for PT/INR Reporting: A Multi-Platform Evaluation Demonstrating the Necessity of Local Verification MinYoung LeeWoo In Lee, So Young Kang, Myeong Hee Kim, Kyu Won cho. Kyung Hee University College of Medicine and Kyung Hee University Hospital at Gangdong, Seoul, South Korea

358

Adding-on Wisely: Hematopathology Reflective Testing in Canada Eric McEvoyEileen R McBride. Children's Hospital of Eastern Ontario, Ottawa, ON, Canada

359

Different methods, same results? A comparison between point-of-care testing and hematology analyzers for hemoglobin and hematocrit measurements. Macarena Ottobre, Rodrigo Arrieta, Ramiro Gosis, Joana Nappe, Maria Victoria Maiocchi, InAcs Marcone. Hospital de NiApos Dr. Ricardo GutiAcrrez, Buenos Aires, Argentina

360

Stakeholder Preferences for Laboratory Result Reporting and Symptom Entry in Emerging Digital Diagnostics Fammi M. Parokkaran1, 2, Henning Nilius1, Michael Nagler 1. 1Department of Clinical Chemistry, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.2Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland

361

Clinical verification of automatic plasma cell immunoselection for FISH analysis Helena Podgornik1, 2, Hermina A1, Karmen DeA¾man1, Ana Doplihar Kebe1, Katarina ReberAiek1. 1Department of Haematology, University Medical Centre Ljubljana, Ljubljana, Slovenia.2Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

362

Overcoming Paperwork Chaos: A Multi-Model Articial Intelligence Framework to Streamline Medical Document Processing Christian Pohlkamp, Gegor HAprmann, Torsten Haferlach, Sven Maschek, Vivian WA¼rf. MLL Munich Leukemia Laboratory, Munich, Germany

363

High-Resolution Age- and Sex-Specific G6PD Reference Intervals Using a Hybrid GMM–KOSMIC Indirect Method on 48, 440 Routine Clinical Results from a National Reference Laboratory Muhammad Shariq Shaikh, Zeeshan Ansar Ahmed. Aga Khan University Hospital, Karachi, Pakistan

364

Extreme hemoglobin discrepancies in samples from peripheral intravenous line starts Christine Snozek, Theresa Kinard. Mayo Clinic Arizona, Phoenix, AZ, USA

365

Impact of sample transport time on cytogenetic evaluability and clinical implications Isolde Summerer, Miriam Lenk, Sophia Prohaska, Verena MA¼hlbacher, Torsten Haferlach. Munich Leukemia Laboratory, MA¼nchen, Germany

366

Evaluating Large Language Model Drafted Clinical Histories from Scanned, Unstructured Medical Records for Hematopathology Practice Chance Walker, Tracy George. ARUP Laboratories, Salt Lake City, UT, USA

367

"Unlocking the Role of Platelet Count: Does It Influence Adhesion Measurements in Collagen-Coated 96-Well Plates?" Mohammad M Algahtani. Security Forces Hospital Makkah, MAKKAH, Saudi Arabia

368

Performance Evaluation of CBC Analysis on miLab™ BCM: A Comparative Study with Sysmex XN Hematology Analyzer Chae Yun Bae1, Soojin Hong1, Mijin Kim1, Joon Suk Choi1, Young-Uk Cho2. 1Noul Co., Ltd, Yongin, South Korea.2Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea